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Volume : III, Issue : VII, August - 2013

Prevalence Of Osteoporosis In Relation To 10 Years Probability Of Major Osteoporotic Fracture And Hip Fracture Risk Using Country Specific Frax Algorithm In Postmenopausal Women In India

Chowdhury Biplob And Bandopadhyaya Sagarika

Published By : Laxmi Book Publication

Abstract :

The purpose of the study was to investigate the prevalence of osteoporosis in relation to assess the 10-year probability percentage of Major Osteoporotic Fracture Risk and to assess the10-year probability percentage of Hip Fracture Risk using FRAX country specific algorithm with bone mineral density. Method: 74 older osteoporotic postmenopausal females ranging the age between 40 to 90 years were randomly selected as the subject of the study. Bone mineral density T-score were obtained by using Ultrasound Bone Densitometry (Omnisense) at distal radius by the experts and technicians. WHO Fracture Risk Assessment Tool (FRAX) INDIA was used to assess the fracture risk probability. FRAX probability calculated with distal radius Bone mineral density was obtained by reference method. Results: There were significant relationship between Body mass index and Bone mineral density. The correlation was highly significant between Bone mineral density and Major Osteoporotic Fracture Risk as well as Bone mineral density and Hip Fracture Risk. Conclusion: The results provide a framework which enhances the assessment of fracture risk in women in combination with Bone mineral density. Fracture risk feedback based on Bone mineral density could potentially make an important contribution to osteoporosis prevention and treatment in postmenopausal women irrespective of age and BMI.

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Cite This Article :

Chowdhury Biplob And Bandopadhyaya Sagarika, (2013). Prevalence Of Osteoporosis In Relation To 10 Years Probability Of Major Osteoporotic Fracture And Hip Fracture Risk Using Country Specific Frax Algorithm In Postmenopausal Women In India. Indian Streams Research Journal, Vol. III, Issue. VII, http://oldisrj.lbp.world/UploadedData/2721.pdf

References :

  1. Strom O, Borgstrom F, Kanis John A, Compston J, Cooper C, McCloskey V E, Jonsson B, Osteoporosis: burden, health care provision and opportunities in the EU. Arch Osteoporos, 6:59–155 (2011)
  2. Kanis JA, on behalf of the World Health Organization Scientific Group (2008) Assessment of osteoporosis at the primary healthcare level. Technical report. WHO Collaborating Centre, University of Sheffield, UK. Available at http://www.shef.ac.uk/FRAX/index.htm
  3. Marshall D, Johnell O, Wedel H: Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures. BMJ,; 312:1254–1259 (1996)
  4. Cummings SR, Melton LJ: Epidemiology and outcomes of osteoporotic fractures. Lancet,; 359:1761–1767.( 2002)
  5. Siris ES, Chen YT, and Abbott TA. Bone mineral density thresholds for pharmacological intervention to prevent fractures. Arch Intern Med,; 164:1108–1112 (2004)
  6. Cauley JA, Wu L, Wampler NS. Clinical risk factors for fractures in multi-ethnic women: the Women's Health Initiative. J Bone Miner Res,; 22:1816–1826.( 2007)
  7. Joop P. W. van den Bergh, Tineke A. C. M. van Geel, Willem F. Lems, Piet P. Geusens. Assessment of Individual Fracture Risk: FRAX and Beyond. Curr Osteoporos Rep,; 8:131–137( 2010)
  8. Kanis JA: Diagnosis of osteoporosis and assessment of fracture risk. Lancet,2002; 359:1929–1936.
  9. Roux C, Reginster JY, Fechtenbaum J. Vertebral fracture risk reduction with strontium ranelate in women with postmenopausal osteoporosis is independent of baseline risk factors. J Bone Miner Res,;21:536–542 (2006)

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