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Volume : II, Issue : XII, January - 2013 EXTRACTION, BIOCHEMICAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF FISH MUCUS M.A.DHOTRE , P.D..BANSODE AND V.S.SHEMBEKAR Published By : Laxmi Book Publication Abstract : Antimicrobial proteins and peptides play key roles in innate immunity and they
had been observed from a wide variety of organisms in the last few years. The present
study was undertaken to characterize antimicrobial peptides from the epidermal mucus
of fishes collected from the Latur fish market. Antimicrobial properties of the fishes
(Channa gachua, Channa punctatus, Cyprinus carpio and Arius dussumieri ) were
tested against pathogenic bacteria and pathogenic fungi. The results of the present
investigation reported that the mucus of the fishes having remarkable antimicrobial
activity. In the present study efforts have been made to find the antimicrobial effect of the
mucus of fresh water and river fishes namely Channa punctatus , Channa gachua,
Cyprinus carpio and Arius dussumieri. Fish mucus was tested against pathogenic
bacteria such as Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris,
Pseudomonas aeruginosa, Staphylococcus aureus, A.niger and C. albicans. The
molecular masses of the peptides were 15 kDa and 200kDa as determined by SDSpolyacrylamide
gel electrophoresis. This peptide had shown very effective activity
against various human pathogens. The present findings suggest that fish mucus has very
good antimicrobial activity against pathogenic microbes. Keywords : Article : Cite This Article : M.A.DHOTRE , P.D..BANSODE AND V.S.SHEMBEKAR, (2013). EXTRACTION, BIOCHEMICAL CHARACTERIZATION AND ANTIMICROBIAL ACTIVITY OF FISH MUCUS. Indian Streams Research Journal, Vol. II, Issue. XII, http://oldisrj.lbp.world/UploadedData/1876.pdf References : - Austin, B. and MacIntosh, D. (1988). Natural antibacterial compounds on the surface of rainbow trout, Salmo gairdneri Richardson. J Fish , 11: 275-277.
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