Scroll to Top

Volume : II, Issue : XII, January - 2013

THE EFFECTS OF AEGLEMARMELOSON DEPRESSION IN WISTAR RATS AND IT'S COMPARISON WITH IMIPRAMINE.

HIMANI , PRATAP SHANKAR , R. C. VERMA , SHARADLEVE , AMODSACHAN AND R. K. DIXIT

Published By : Laxmi Book Publication

Abstract :

Present study was done to see the antidepressant effect of Aeglemarmelosand its comparison with the standard treatment with imipramine in wistar rats. The study was done using Forced swim test (FST). From the results of present study it is concluded that Aeglemarmelos has antidepressant activity as shown by the results of force swim test. Aeglemarmelos extract at both the doses (100 mg/Kg, 200 mg/Kg, p.o) significantly decreased the duration of immobility, indicating an antidepressant activity. Comparatively, higher dose has been found to be more effective than lower dose.

Keywords :


Article :


Cite This Article :

HIMANI , PRATAP SHANKAR , R. C. VERMA , SHARADLEVE , AMODSACHAN AND R. K. DIXIT, (2013). THE EFFECTS OF AEGLEMARMELOSON DEPRESSION IN WISTAR RATS AND IT'S COMPARISON WITH IMIPRAMINE.. Indian Streams Research Journal, Vol. II, Issue. XII, http://oldisrj.lbp.world/UploadedData/1875.pdf

References :

  1. Andrews JM, Nemeroff CB (1994). Contemporary management of depression. Am J Med 97:24S–32S
  2. Borsini F, Meli A (1988). Is the forced swimming test a suitable model for revealing antidepressant activity? Psychopharmacology (Berl.) 94:147–160
  3. France CP, Lin J-X, Owens WA,Koek W, Toney GM, Daws LC (2009). Reduced effectiveness of escitalopram in the forced swimming test is associated with increased serotonin clearance rate in foodrestricted rats.IntJ Neuropsychopharmacol 12:731–736.
  4. Chimenti F,Cottiglia F,Bonsignore L,Casu L,Casu M,Floris C,Secci D,Bolasco A,Chimenti P,Granese A,Befani O,Turini P,Alcaro S, Ortuso F,Trombetta G,Loizzo A, Guarino I (2006).Quercetin as the active principle of Hypericumhircinumexerts a selective inhibitory activity against MAO-A: Extraction, biological analysis, and computational study. J Nat Prod69:945-949.

Article Post Production

Article Indexed In

Comments :

Enter Name :
Email ID :
Comments :

Previous Comments :

Creative Commons License
Indian Streams Research Journal by Laxmi Book Publication is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at http://oldisrj.lbp.world/Default.aspx.
Permissions beyond the scope of this license may be available at http://oldisrj.lbp.world/Default.aspx
Copyright � 2014 Indian Streams Research Journal. All rights reserved
Looking for information? Browse our FAQs, tour our sitemap, or contact ISRJ
Read our Privacy Policy Statement and Plagairism Policy. Use of this site signifies your agreement to the Terms of Use