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Volume : V, Issue : V, June - 2015

BENEFICIAL EFFECT OF ELLAGIC ACID AGAINST IRON INDUCED OXIDATIVE DAMAGE IN THE LIVER OF RATS

S. Palani, D. Santhakumari

By : Laxmi Book Publication

Abstract :

The strength of the modern literary imagination lies in its evocation of the individual’s predicament in terms of the alienation, exile or search for identity. Literature of the Third World is no exception to this general tendency in modern writing in which the theme of individual’s predicament in the form of rootlessness, crisis of identity mainly lying behind the desperate affirmation of traditional culture has been explicitly explored. Naipaul's fictional work is concerned with the intricate fate of the individual, societies and cultures. His recurring themes are the collision of cultures and the resultant ambiguities in human adjustment, the colonial situation that produces a special kind of human psychoisis when man is eager to search a niche for himself at any cost.

Keywords :


Article :


Cite This Article :

S. Palani, D. Santhakumari(2015). BENEFICIAL EFFECT OF ELLAGIC ACID AGAINST IRON INDUCED OXIDATIVE DAMAGE IN THE LIVER OF RATS . Indian Streams Research Journal, Vol. V, Issue. V, http://isrj.org/UploadedData/6739.pdf

References :

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  30. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  31. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  32. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  33. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  34. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  35. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  36. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  37. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  39. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  40. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  41. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  42. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  43. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  44. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  45. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  46. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  47. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  48. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  50. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  51. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  52. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  53. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  54. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  55. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  56. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  58. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  59. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  60. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  61. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  62. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  63. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  64. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  65. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  66. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  67. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  68. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  69. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  70. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  71. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  73. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  74. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  75. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  76. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  77. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  78. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  79. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  80. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  82. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  83. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  84. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  85. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  86. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  87. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  88. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  89. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  90. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  91. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  93. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  94. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  95. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  96. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  97. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  98. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  99. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  100. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  101. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  102. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  104. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  105. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  106. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  107. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  108. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  109. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  110. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  111. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  112. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  113. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  115. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  116. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  117. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  118. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  119. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  120. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  121. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  122. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  123. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  125. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  126. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  127. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  128. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  129. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  130. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  131. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  132. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  133. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  134. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  135. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  136. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  138. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  139. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  140. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  141. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  142. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  143. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  144. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  145. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  146. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  147. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  149. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  150. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  151. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  152. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  153. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  154. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  155. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  156. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  157. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  158. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  160. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  161. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  162. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  163. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  164. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  165. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  166. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  167. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  168. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  169. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  171. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  172. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  173. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  174. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  175. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  176. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  177. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  178. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  179. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  180. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  181. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  182. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  183. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  185. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  186. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  187. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  188. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  189. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  190. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  191. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  192. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  194. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  195. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  196. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  197. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  198. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  199. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  200. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  201. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  202. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  203. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  204. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  205. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  206. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  207. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  209. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  210. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  211. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  212. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  213. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  215. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  216. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  217. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  218. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  219. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  220. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  221. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  222. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  223. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  224. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  226. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  227. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  228. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  229. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  230. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  231. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  232. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  233. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  234. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  235. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  237. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  238. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  239. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  240. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  241. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  242. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  243. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  244. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  245. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  246. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  247. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).
  249. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  250. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  251. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  252. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  253. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  254. Niederen C, Fisher R, Sonnenberg A, Stremmel W, Trampisch HJ and Strohmeyer G, Survival and cause of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis, N.Eng.J.Med. 313, 1256-1262, (1985).
  255. Shimuzu M, Morito S, Mayano Y and Yamada A, Relationship between hepatic glutathione content and carbon tetrachloride-induced hepatotoxicity invivo. Toxicol. Leb. (Austria), 47, 95-102, (1989).
  256. Naika GH, Priyadarsinia KI, Naika DB, Gangabhagirathib R, Mohan H, Studies on the aqueous extract of terminalia chebula as a potent antioxidant and a probable radioprotector, phytomedicine. 11, 530-538, (2004).
  257. Stremmel W, Kley HK, Kruskemper HL and Strohmeyer G, Differing abnormalities in estrogen and androgen and insulin metabolism in idiopathic hemochromatosis versus alcoholic liver disease. Semin. Liver Dis. 5, 84-93, (1985).
  259. Weintraub LR, Gorel A, Grasso J, Franzblau C, Sullivan A, Sullivan S, Pathogenesis of hepatic fibrosis in experimental iron overload. Br.J.Haematol. 59, 321-331, (1985).
  260. Britton RS, Bacon BR and Recknagal RO, Lipid peroxidation and associated hepatic organelle dysfunction in iron overload. Chem.Phys.Lipids. 45,207-239, (1987).
  261. Ryan TP and Aust SD, The role of iron in oxygen mediated toxicities. Crit.Rev.Toxicol. 22, 119-141, (1992).
  262. Kehrer, JP, The haber-weiss reaction and mechanisms of toxicity. Toxicology. 149, 43-50, (2000).
  263. Halliwell B, Iron and damage to biomolecules, in; Lauffer,R.B.(Ed.), Iron and human disease. CRC,Boca Raton,pp, 209-236, (1992).
  264. Wills ED, Biochemical diagnosis. In; E.D.Wills (Ed.), Biochemical basis of medicine, Write, Bristol, England, pp. 489-499, (1985).

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