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Volume : IV, Issue : V, June - 2014

STUDY THE GENDER DIFFERENCES IN ADHD CHILDREN: IS THE RESPONSE TO CNS STIMULANTS A CASE OF ONE FITS BOTH?

Mohamed R. El-Fiky, Gihan M. El-Nahas, Heba H. El-Shahawy , Mohamed F. Abdel Aziz , Dalia H. Ali and Nawal M. Khalifa

By : Laxmi Book Publication

Abstract :

Attention-Deficit-Hyperactivity Disorder (ADHD) is one of the most prevalent disorders in school children worldwide, with social and academic functioning impairments and persistence into adulthood that appears to be more in boys than in girls (3:1). While CNS stimulants are the first line of treatment, improving up to 70-90% cases, their use had created controversies questioning their risks. Gender mind treatment criteria to test differences in response, side effects profile, dose of response, and dosing schedule were the aims of the current work. Consenting 21 males and 10 females have participated in the study, with mean age of 8.2+3, 8.4+2.2 years respectively, 100.8, 106.5 IQ respectively and no chronic comorbid physical or mental contra indications. They were screened by diagnostic tools (Mini International Neuropsychiatric Interview, Stanford Binet and Wechster Intelligence Scales, Vigil Continuous Performance Test, Conner's Parent and Teacher Rating Scales, and Stimulants Side effects Rating Scale). The dosage of the selected stimulant (Methylphenidate) was estimated based on the subjects' weight (0.75, 0.76 mg/kg respectively). Short-term follow-up of 6 weeks reevaluated improvement and side effects developed. Combined type of ADHD was the most prevailing variant, with higher severity in females, namely inattention, reflected in particular on Teacher Rating Scale of Conner. In the noted marked improvement, there were undetected statistically significant gender differences, however in the individual symptoms females recorded less improvement and showed more talk less and less interest as side effects. Conclusive evidences for the role of gender in ADHD require by passing methodological limitations as well as confounding factors.

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Cite This Article :

Mohamed R. El-Fiky, Gihan M. El-Nahas, Heba H. El-Shahawy , Mohamed F. Abdel Aziz , Dalia H. Ali and Nawal M. Khalifa(2014). STUDY THE GENDER DIFFERENCES IN ADHD CHILDREN: IS THE RESPONSE TO CNS STIMULANTS A CASE OF ONE FITS BOTH?. Indian Streams Research Journal, Vol. IV, Issue. V, http://isrj.org/UploadedData/4930.pdf

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