Indian Streams Research Journal

Volume : IV, Issue : III, April - 2014

THE POTENTIAL ANTICANCER ACTIVITYOFSAUDI ARABIA AJW AH DA TES (PHOENIX DACTYLIFERA)

Mohammad Safar Al-Shahrani , Hussein A. Almehdar

By : Laxmi Book Publication

Abstract :

he date palm (Phoenix dactylifera L.) is considered one of the most important commercial crops in the Arab world. A trial to obtain a natural potentially active extract with anticancer activity from the Saudi Arabia plant and more safe for human. Ehrlich Ascites Carcinoma (EAC) was used to evaluate MARE on mice after 24 and 48 hours of tumor inoculation at levels of (200mg/ml) as antitumor activity to show the sufficient value which causes EAC cells nonviable. The treatment with MARE did not appear a remarkable toxicity on the mice which resulting in the lowering percentage of mortality. The results indicated the life-span of mice groups after 60 days of EAC inoculated on the female Swiss albino mice. The female Albino mice with EAC (Group II), all mice died of carcinoma within 31 ± 3.46 day of inoculation; while the concurrent administration MARE plus the EAC-bearing hosts and MARE alone (Group III and IV) resulted in an increase (P < 0.001) in mean survival of the animals; maximum life-span being 53 ± 0.35 day . This significant result of mean life-span in (Group III and IV) comparing with lifespan in (Group II) confirmed the efficiency of MARE against EAC.

Keywords :

• Date palm (Phoenix dactylifera L.)
• Ehrlich Ascites Carcinoma
• albino mice anticancer activity
• Date palm (Phoenix dactylifera L.)
• Ehrlich Ascites Carcinoma
• albino mice anticancer activity
• Date palm (Phoenix dactylifera L.)
• Ehrlich Ascites Carcinoma
• albino mice anticancer activity

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References :

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195. Abou-Elella, F . M. 2005. Molecular Biology of Cancer Cells as affected by Some Natural Compounds. M.Sc. Thesis, Faculty
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213. Journal of Food Science and Nutrition, 54: 247–259.
214. Abou-Elella, F . M. 2005. Molecular Biology of Cancer Cells as affected by Some Natural Compounds. M.Sc. Thesis, Faculty
215. Al-Farsi, M.; Al asalvar, C.; Morris, A.; Baron, M. and shahidi, F . 2005. Comparison of antioxidant activity , anthocyanins,
216. dactylifera in Gentamicin-Induced Nephrotoxicity Pharmaceutical Biology, 46(4): p227.
217. carotenoids and Phenolics of three native fresh and sundried date Phoenix dactylifera L. V arieties grown in Oman. Journal of
218. Agricultural and Food Chemistry, 53: 7592-7599.
219. Al-Shahib, W. and Marshall, R.J. 2003. The fruit of the date palm: its possible use as the best food for the future. International
220. Journal of Food Science and Nutrition, 54: 247–259.
221. carotenoids and Phenolics of three native fresh and sundried date Phoenix dactylifera L. V arieties grown in Oman. Journal of
222. Abou-Elella, F . M. 2005. Molecular Biology of Cancer Cells as affected by Some Natural Compounds. M.Sc. Thesis, Faculty
223. Agricultural and Food Chemistry, 53: 7592-7599.
224. Al-Shahib, W. and Marshall, R.J. 2003. The fruit of the date palm: its possible use as the best food for the future. International
225. Abou-Elella, F . M. 2005. Molecular Biology of Cancer Cells as affected by Some Natural Compounds. M.Sc. Thesis, Faculty
226. Al-Nasemi, M.N. 1988. The Prophet Medicine & Modern Science part 3 (Daar Al-Resalah).
227. Journal of Food Science and Nutrition, 54: 247–259.
228. carotenoids and Phenolics of three native fresh and sundried date Phoenix dactylifera L. V arieties grown in Oman. Journal of
229. carotenoids and Phenolics of three native fresh and sundried date Phoenix dactylifera L. V arieties grown in Oman. Journal of
230. Journal of Food Science and Nutrition, 54: 247–259.
231. Al-Nasemi, M.N. 1988. The Prophet Medicine & Modern Science part 3 (Daar Al-Resalah).
232. of Science, Cairo University, Egypt.
233. Agricultural and Food Chemistry, 53: 7592-7599.
234. Al-Shahib, W. and Marshall, R.J. 2003. The fruit of the date palm: its possible use as the best food for the future. International
235. Al-Qarawi, A.A.; Abdel-Rahman, H.; Mousa, H.M.; Ali B.H. and El-Mougy S.A. 2008. Nephroprotective Action of Phoenix
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237. carotenoids and Phenolics of three native fresh and sundried date Phoenix dactylifera L. V arieties grown in Oman. Journal of
238. Journal of Food Science and Nutrition, 54: 247–259.
239. of Science, Cairo University, Egypt.
240. Abou-Elella, F . M. 2005. Molecular Biology of Cancer Cells as affected by Some Natural Compounds. M.Sc. Thesis, Faculty
241. Al-Farsi, M.; Al asalvar, C.; Morris, A.; Baron, M. and shahidi, F . 2005. Comparison of antioxidant activity , anthocyanins,
242. Abou-Elella, F . M. 2005. Molecular Biology of Cancer Cells as affected by Some Natural Compounds. M.Sc. Thesis, Faculty
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