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Volume : IV, Issue : I, February - 2014

BIOLOGICAL ACTIVITY OF THE EGYPTIAN MEDICINAL PLANTS: PART 3 ANTI-OXIDANT, CYTOTOXICITY, ANTI-DIABETIC ACTIVITIES AND CONSTITUENTS OF BETA VULGARIS SUBSP. PERENNIS

Abdel-Monem Ateya, Fawkeya Abbas and Rasha Hamza

By : Laxmi Book Publication

Abstract :

Several columns chromatography of the ethyl acetate fraction of Beta vulgaris subsp. perennis (family Chenopodiacaea) resulted in isolation of quercetin, 4'-hydroxy-5methoxy-6,7- methylenedioxy flavanone, quercetrin and rutin. In addition to the phenolic acids: syrinigic, ferulic and the monoterpene dehydro-vomifoliol. The structure of these compounds was confirmed by spectral methods as well as comparison with reported data. The antioxidant activity indicated moderate activity SC 8.5μg/ml, compared with that of vitamin C (SC 1.24μg/ml). The total ethanolic extract of Beta 50 50 vulgaris subsp. perennis exhibited a mild cytotoxic activity (IC 60.26ìg/ml compared with 50 Doxorubicin IC 21.4μg/ml) against Hep-G2 cells. The ethyl acetate extract (400mg/kg) has nearly the 50 same potency as glibenclamide (5mg/kg), but the aqueous extract (400mg/kg) has higher potency than glibenclamide. The aqueous extract significantly decreased rat hind paw edema thickness compared to control group. Ethanolic extract has no anti-inflammatory effect.

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    Cite This Article :

    Abdel-Monem Ateya, Fawkeya Abbas and Rasha Hamza(2014). BIOLOGICAL ACTIVITY OF THE EGYPTIAN MEDICINAL PLANTS: PART 3 ANTI-OXIDANT, CYTOTOXICITY, ANTI-DIABETIC ACTIVITIES AND CONSTITUENTS OF BETA VULGARIS SUBSP. PERENNIS. Indian Streams Research Journal, Vol. IV, Issue. I, http://isrj.org/UploadedData/4260.pdf

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