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Volume : III, Issue : V, June - 2013 SYNTHESIS OF INDOLYL IMIDAZOLES USING PEG-400 AS A RECYCLABLE REACTION MEDIUM AT ROOM TEMPERATURE Ashok T. Kadam , Pravin S. Bhale and Sakharam B. Dongare DOI : 10.9780/22307850, Published By : Laxmi Book Publication Abstract : An efficient and green method for synthesis of imidazole containing indole
nucleus has been achieved by the reaction between 3-bromoacetyl indole, aniline,
various aldehydes and ammonium acetate using PEG-400 as a recyclable reaction
medium at room temperature. The method is simple, efficient and environmental benign.
The compounds obtained are in excellent yield with high purity by easy work up. Keywords : Article : Cite This Article : Ashok T. Kadam , Pravin S. Bhale and Sakharam B. Dongare, (2013). SYNTHESIS OF INDOLYL IMIDAZOLES USING PEG-400 AS A RECYCLABLE REACTION MEDIUM AT ROOM TEMPERATURE. Indian Streams Research Journal, Vol. III, Issue. V, DOI : 10.9780/22307850, http://oldisrj.lbp.world/UploadedData/2555.pdf References : - J.G. Lambardino, E.H. Wiseman, J. Med. Chem. 17 (1974) 1182.
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