DOI Prefix : 10.9780 | Journal DOI : 10.9780/22307850
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Volume : II, Issue : IX, October - 2012

Studies On Blood Profile In Thalassaemia Patients Before And After Blood Transfusion In And Around Rahata, Ahmednagar

A. J. Dhembare , A. B. Gholap , S. N. Karjule and Jayshree Dhumal

DOI : 10.9780/22307850, Published By : Laxmi Book Publication

Abstract :

The present study was undertaken to evaluate the effect of blood transfusion in thalassaemia patient in urban and rural area of Rahata during July 2011 to February 2012. Thalassaemic fifty patients were selected and regularly blood transfusion was carried out. Pre- and post-transfusion Hb, RBC, WBC, HCT, platelets, MCV, MCH, MCHC, urea, sugar, creatinine and cholesterol were evaluated. The obtained results are discussed. Also symptoms, epidemiology, and possible physiology discussed.

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Cite This Article :

A. J. Dhembare , A. B. Gholap , S. N. Karjule and Jayshree Dhumal, (2012). Studies On Blood Profile In Thalassaemia Patients Before And After Blood Transfusion In And Around Rahata, Ahmednagar. Indian Streams Research Journal, Vol. II, Issue. IX, DOI : 10.9780/22307850, http://oldisrj.lbp.world/UploadedData/1459.pdf

References :

  1. Modiano, G. (1991). Protection against malaria morbidity - Near fixation of the Alpha Thalassaemia gene in a Nepalese population. Am. J. Human Genetics, 48 : 390–397.
  2. Terrenato, L. (1988). Decreased malaria morbidity in the Tharu people compared to sympatric populations in Nepal. Annals of Tropical Medicine & Parasit., 82 : 1–11.
  3. Samavat, A. and Modell, B. (2004). Iranian national thalassaemia screening programme. BMJ (Clinical Research Ed.) 329: 1134–7.
  4. Leung, T. N., Lau, T. K. and Chung, T. K. (2005). Thalassaemia screening in pregnancy. Curr. Opinion in Obstetrics & Gyneco. 17 : 129–34.
  5. Ladis, V., Theodorides, C., Palamidou, F., Frissitus, C., Berdousi, H. and Kattamis, C. (1998). Glucose disturbances and rgulation with gibenclamide in Thalassaemia. J. Ped. Endocr. Metab. 11: 871-878.
  6. Weatherall, David J, (1991). Chapter 47. The Thalassaemias: Disorders of Globin Synthesis (Chapter). Lichtman MA, Kipps TJ, Seligsohn U, Kaushansky K, Prchal, JT: Williams Hematology, 8: 32-38
  7. Tesoriere, L., Allegra, M., Butera, D., Gentile, C. and Livrea, M. A. (2006). Cytoprotective effects of the antioxidant phytochemical indicaxanthin in beta-thalassaemia red blood cells. Free Radical Res. 40: 753–61.
  8. Chern, J., Lin, K. H., Lu, M.Y., Lin, D. J., Lin, K. S., Chen, J. D. and Fu, C. C. (2001). Abnormal glucose tolerance in transfusion dependent â-Thalassemic Patients. Diabetes Care, 24: 850-854.
  9. Dmochowski, K., Finegood, D.T., Francombe, W., Tyler. B. and Zinman, B. (1993). Factors determining glucose tolerance in patients with Thalassaemia major. J. Clin. Endocrinol. Metab, 77: 478-483.
  10. Wambua, S., Mwangi, T.W. and Kortok, M. (2006). The effect of alpha+-thalassaemia on the incidence of malaria and other diseases in children living on the coast of Kenya. PLoS Medicine 3 : 158.
  11. Tassiopoulos, S., Deftereos, S. and Konstantopoulos, K, (2005). Does heterozygous beta-thalassaemia confer a protection against coronary artery disease? Annals New York Acad. of Scie., 1054: 467–70.
  12. Borgna Pignatti, C., De Stefano, P., Zonta, L., Vullo, C., De Sanctis, V., Melevendi, C., Nuselli, A., Masera, G., Terzoli, S., Gabutti, V. and Piga, A. (1985). Growth and sexual maturation in Thalassaemia major. J. Pediatr, 106:150- 155.
  13. Skordis, N., Christou, S., Koliou, M., Pavlides, N. and Angastiniotis, M. (1998). Fertility in female patients with Thalassaemia. J. Ped. Endocrinol. Metab. 11:935-943.
  14. Bharucha, C., Meyer, H., Moody, A. and Camann, R. H. (1976). Handbook of Medical Laboratory Techniques. Wesley Press Mysore, India. pp: 61.
  15. ICSH, (1985). International Committee for Standardization in Haematology, Recommendation for reference method for determination by centrifugation of packed cell volume of blood. J. Clinic. Pathol. 33,1.
  16. Bain, B. J. (1985). Platelet count and platelet size in males and females. Scandinavian J. Haematology 35, 77.
  17. Godkar, B. (1994). Textbook of Medical Laboratory Technologies. Publ. Bhalini Publishing House, Bombay pp:688.
  18. . George, R., Kanppe, G., Geri, H., Venze, M. and Stahl, F. (1999). J. Endocrinol. Investi., 22, 241. 19. Zlatki, A., Zak, B. and Boyle, A. J. (1953). J. Lab. Clin. Med., 41, 486..
  19. De Sanctis, V., Vullo, C., Katz, M., Wonke, B., Tanaw, R. and Bagni, B. (1988). Gonadal function in patients with â-Thalassaemia major. J. Clin. Pathol., 41:133-137.
  20. De Sanctis, V., Vullo, C., Katz, M., Wonke, B., Nannetti, C. and Bagni, B. (1998). Induction of spermatogenesis in Thalassaemia. Fertility Sterility, 50: 969-975.

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